This presentation was delivered on September 25, 2025, at the launching
of the Food Literacy & Sustainable Nutrition (FOLSUN) Initiative at the
University of Mauritius. Prof. William Chen from Nanyang Technological
University (NTU) addressed critical challenges and opportunities in
transforming our food systems through alternative proteins and circular economy
approaches. The Current Food System
Crisis
The Fundamental Challenge
The global food system faces mounting pressure from multiple directions.
With the world population projected to reach 10 billion by 2050, conventional
meat production systems are increasingly unsustainable. The environmental and
health issues associated with traditional animal agriculture—including
greenhouse gas emissions, land use, water consumption, and public health
concerns—necessitate a fundamental rethinking of how we produce protein.
Constraints and Needs
The presentation establishes that our current food system operates under
significant constraints: limited agricultural land, water scarcity, climate
change impacts, and the inefficiency of converting plant calories into animal
protein. These constraints create an urgent need for innovative solutions that
can deliver adequate nutrition while reducing environmental impact.
Alternative Protein
Sources: A Detailed Analysis
1. Plant-Based Foods and
Meat Alternatives
Plant-Based Foods: The Advantages
Prof. Chen distinguishes between whole plant-based foods and processed
plant-based meat products. Traditional plant-based foods offer several
compelling advantages:
- Nutrient
density: Rich in vitamins, minerals, fiber, and
phytonutrients
- Consumer
familiarity: People already understand and consume
vegetables, legumes, grains, and nuts
- Minimal
processing: Can be consumed with fewer industrial
processing steps
- Cost-effectiveness:
Generally more affordable than both animal meat and processed alternatives
- True
alternatives: Represent genuine dietary diversity rather
than meat imitations
Plant-Based Meats: The Reality Check
However, highly processed plant-based meat alternatives face significant
challenges:
- Hyper-processed
nature: Require extensive industrial processing,
multiple ingredients, and additives to achieve meat-like texture and
flavor
- Identity
crisis: Despite marketing, they are fundamentally
not meat, which creates cognitive dissonance for consumers
- Premium
pricing: Often more expensive than conventional
animal meat, creating a barrier to widespread adoption
- Low
consumer buy-in: Many consumers remain skeptical or
uninterested, limiting market growth beyond early adopters
This dichotomy highlights a critical tension in the alternative protein
space: the trade-off between creating familiar meat-like experiences and
maintaining the inherent benefits of plant-based eating.

2. Cultivated Meat
(Cell-Based/Lab-Grown Meat)
Regulatory Landscape
The cultivated meat sector presents a fascinating study in global
regulatory divergence:
- Singapore
and USA: Have granted regulatory approval,
positioning themselves as innovation leaders
- Italy:
Has banned cultivated meat by law, citing cultural and agricultural
preservation concerns
- This
regulatory patchwork creates uncertainty for investors and companies
attempting to scale
The Urban Solution Proposition
Cultivated meat is often positioned as an urban solution because it
could theoretically:
- Reduce
the land footprint of protein production
- Be
produced closer to consumption centers
- Minimize
transportation and associated emissions
- Address
sustainability concerns in land-scarce environments
Critical Barriers
Despite its promise, cultivated meat faces formidable obstacles:
- Scale-up
bottleneck: Moving from laboratory production to
industrial-scale manufacturing remains technically challenging and
economically unproven
- Cost
structure: Production costs remain prohibitively high,
with questions about whether costs can ever reach parity with conventional
meat
- Consumer
acceptance: Many consumers express discomfort with
"lab-grown" food, raising questions about willingness to pay
premium prices
3. Biomass Fermentation and
Precision Fermentation
Prof. Chen identifies fermentation technologies as emerging
alternatives, though he poses the critical question: "High Cost?"
This suggests that while these technologies show promise, their economic
viability remains uncertain.
Biomass Fermentation: Uses microorganisms (like fungi or
bacteria) grown on various feedstocks to produce protein-rich biomass.
Precision Fermentation: Engineers microorganisms
to produce specific proteins, such as dairy proteins without cows, offering
highly targeted nutrition solutions.
4. Alternative Food Sources
from Nature
The "Real Solutions" Question
Prof. Chen provocatively asks whether these natural alternatives
represent "Real Solutions?!" suggesting cautious optimism:
Microalgae
- High
protein content and rapid growth rates
- Can
be cultivated in non-arable land
- Rich
in omega-3 fatty acids and other nutrients
- Challenges
include taste, digestibility, and processing costs
Edible Insects
- Extremely
efficient feed conversion ratios
- High
protein and micronutrient content
- Low
environmental footprint
- Major
barrier: cultural acceptance in Western markets
Mushrooms
- Increasing
consumption as meat alternatives
- Low
in calories and cholesterol-free
- Provide
umami flavor and meaty texture
- Offer
documented health benefits
- Already
culturally accepted in most markets
The mushroom sector appears particularly promising because it overcomes
the acceptance barrier while delivering nutritional and sustainability
benefits.
Food Circular Economy:
Closing the Loop
The Waste Crisis in Food
Manufacturing
The presentation reveals that significant food loss occurs at every
stage of the food value chain:
- Pre-harvest/slaughter:
Agricultural waste, damaged crops
- On-farm
post-harvest/slaughter operations: Processing waste,
unusable parts
- Transport,
storage, and distribution: Spoilage, damage
- Processing
and packaging: Manufacturing side-streams, off-cuts,
by-products
The Circular Economy Vision
Prof. Chen presents a comprehensive framework for closed-loop
upcycling, which he intriguingly labels as "too easy and too
good?" This rhetorical question suggests that while the concept is
compelling, implementation faces hidden complexities.
The Circular System Components:
Inputs: Agricultural and food manufacturing operations generate side-streams
(a more positive term than "waste")
Food Manufacturing Side-Streams (FMSS): Materials that are
currently discarded but contain valuable ingredients:
- Okara:
The fibrous residue from soy milk and tofu production, rich in protein and
fiber
- Brewer's
spent grains: Barley remnants from beer brewing, high in
protein and fiber
Transformation Process: These materials are
processed to extract or utilize valuable components
Reintegration: Valuable ingredients are returned to the food chain for human
consumption
Alternative Applications: Materials unsuitable for
food can be used in other sectors (animal feed, biofuels, materials)
Residual Waste: Only true waste that cannot be utilized remains in the system
Food Manufacturing
Side-Streams: A Balanced Perspective
The presentation acknowledges both advantages and challenges of
utilizing FMSS through a "quad-modal hazard dynamics" approach, which
considers:
- Biological
hazards: Microbial contamination risks
- Chemical
hazards: Pesticide residues, heavy metals, processing
chemicals
- Physical
hazards: Foreign materials, contaminants
- Nutritional/allergen
concerns: Anti-nutritional factors, allergenic
proteins
This nuanced approach recognizes that food waste valorization isn't
automatically safe—it requires rigorous assessment and appropriate processing.
Food Safety Risk Assessment
Framework
The Critical Importance of
Safety
As alternative foods and circular economy approaches proliferate, Prof.
Chen emphasizes that safety cannot be an afterthought. Novel foods require
novel safety assessment approaches.
General Framework vs. Novel
Foods Framework
The presentation contrasts:
Traditional Food Safety Risk Assessment:
- Hazard
identification
- Hazard
characterization
- Exposure
assessment
- Risk
characterization
- Well-established
for conventional foods
Novel Foods Risk Assessment Framework:
- Must
address unique challenges of foods with no history of safe use
- Requires
evaluation of production processes (e.g., genetic modifications, cell
culture conditions)
- Must
consider novel compounds and interactions
- Needs
to assess allergenicity and toxicology of unfamiliar proteins
New Approach Methodologies
(NAMs)
Traditional food safety testing relies heavily on animal testing, which
is:
- Time-consuming
and expensive
- Raises
ethical concerns
- May
not accurately predict human responses
NAMs offer alternatives:
- In
vitro (test tube) testing systems
- Computational
modeling and simulation
- Human
cell-based assays
- Organ-on-a-chip
technologies
- Artificial
intelligence for predictive toxicology
These approaches can accelerate safety assessment while reducing animal
testing and potentially improving human relevance.
The FRESH-WHO Initiative
A Global Collaboration for
Food Safety
Prof. Chen concludes by presenting the FRESH (Food safety Risk
assessment for Eating and living Safely and Healthily) initiative's
collaboration with the World Health Organization.
Core Components
Global Perspectives: Bringing together international expertise
and multilevel support to address food safety as a universal concern
Local Priorities: Ensuring that global frameworks can be
adapted to regional needs and constraints
Working Areas
- Novel
Foods and Production Systems: Developing
assessment frameworks for cultivated meat, precision fermentation
products, insect proteins, and other emerging foods
- Nutrition-Food
Safety Integration: Recognizing that
safety and nutrition cannot be separated—a food that is safe but
nutritionally poor, or nutritious but unsafe, both fail to serve public
health
- New Approach
Methodologies (NAMs): Implementing
cutting-edge testing methods to accelerate and improve safety assessment
- Artificial
Intelligence and Digital Innovations: Leveraging AI for
predictive modeling, big data analysis, and rapid risk assessment
The Ultimate Goal
The initiative aims to create "a dynamic and comprehensive
next-generation food risk assessment framework and related food control
components that are effective and responsive to the evolving landscape of food
systems, thereby ensuring continuous protection of global public health."
This vision recognizes that food systems are rapidly evolving, and
safety frameworks must be equally dynamic—not static regulations that quickly
become outdated.
Conclusion: Navigating
Complexity
Prof. Chen's presentation reveals that the transition to sustainable
food systems involves navigating complex trade-offs:
- Innovation
vs. Acceptance: Cutting-edge technologies may struggle with
consumer adoption
- Cost
vs. Sustainability: More sustainable
options often carry premium prices
- Processing
vs. Naturalness: Creating meat alternatives requires
processing that some consumers reject
- Speed
vs. Safety: Rapid innovation must be balanced with
thorough safety assessment
The path forward requires not just technological innovation, but also:
- Robust
regulatory frameworks that enable innovation while ensuring safety
- Economic
models that make sustainable options accessible
- Consumer
education to build acceptance
- International
cooperation to share knowledge and harmonize standards
- Integration
of nutrition and safety considerations from the earliest stages of
development
The presentation ultimately argues that alternative foods and circular
economy approaches are essential tools for feeding 10 billion people
sustainably, but their success depends on addressing economic, regulatory,
safety, and consumer acceptance challenges with the same rigor applied to
technological innovation.